A 61-year-old man with asymptomatic, bilateral lung masses.

The Clinical Case of the month is a regular educational feature presented by the Louisiana State University Department of Medicine. Medical students, residents, postdoctoral fellows, and faculty collaborate in the preparation of these manuscripts. After reading this article, physicians should be better able to: 1) Increase awareness of the incidence and types of opportunistic infections which may be associated with immune compromised states; 2) Identify the immunocompromised state induced by treatment with tumor necrosis factoralpha antagonists and the increased risk of cryptococcal pneumonia in patients receiving such agents. Estimated time to complete this activity is one (1) hour. Tayyab Rehman, MD; Juzar Ali, MD, FRCP(C); and Fred A. Lopez, MD (Section Editor)